A worker handles a bottle of Merck & Co. and Ridgeback Biotherapeutics LPs Molnupiravir antiviral medication in a warehouse in Shoham, Israel, on Jan. 18, 2022. A fourth dose of the Pfizer-BioNTech vaccine was insufficient to prevent infection with the omicron variant of Covid-19, according to preliminary data from a trial...
The chemical structures of Molnupiravir, NHC and EIDD-1931-triphopsphate.
View full-text article in PMCFront Immunol . 2022 Apr 4;13:855496. doi: 10.3389/fimmu.2022.855496 Copyright and License information The chemical structures of Molnupiravir, NHC and EIDD-1931-triphopsphate.(A) Molnupiravir, Beta-D-N4-hydroxycytidine-5’-isopropyl ester (MK-4482/EIDD-2801) is a bioactive prodrug of NHC (EIDD-1931). (B) Beta-D-N4-hydroxycytidine(NHC,EIDD-1931) is an orally bioavailable ribonucleoside analogue, which has broad-spectrum activity against a variety of RNA viruses. (C) EIDD-triphosphate can...
Buyer beware: molnupiravir may damage DNA
Buyer beware: molnupiravir may damage DNA J. V. van Schalkwyk Published in British medical journal 4 November 2021 Medicine TLDR There is a certain irony that vaccine shy people who have believed the untruth that vaccines against SARS-CoV-2 alter DNA seem poised to reach for a perceived “alternative” that may actually alter their...